CV,Professional Seeking Opportunities In Biotech And Pharma Within Eur
Biochemical Engineer with over 4 years of experience in working with multi-disciplinary teams in the pursuit of world-class research pertaining to Oncology. Team-oriented leader with proven success in developing, managing, and executing innovative projects which identify, characterize, and target non-coding RNAs in various types of cancer.
Expertise includes:
• Multi-dimensional RNA-based Project Management & Leadership
• Non-coding RNA Therapeutics Research
• Protocol & Milestone Development
Texas, United States - View on map
Romanian
Pharmaceutical and Science
english, french, german, romanian
Belgium, Denmark, Finland, France, Germany, Hungary, Italy, Netherlands, Norway, Poland, portugal, Romania, spain, Sweden, switzerland, United Kingdom
Profile
Biochemical Engineer with over 4 years of experience in working with multi-disciplinary teams in the pursuit of world-class research pertaining to Oncology. Team-oriented leader with proven success in developing, managing, and executing innovative projects which identify, characterize, and target non-coding RNAs in various types of cancer.
Expertise includes:
• Multi-dimensional RNA-based Project Management & Leadership
• Non-coding RNA Therapeutics Research
• Protocol & Milestone Development & Execution
• Data Aggregation & Analysis
• Negotiation & Collaboration Skills
• Scientific & Business Communication & Presentation
• Quality Improvement and Assurance
Work Experience
• Dates: Dec 2013 – present
• Name and address of employer:M.D. Anderson Cancer Center, Houston, Texas, U.S.A.
• Occupation or position held: Postdoctoral Fellow
• Main activities and responsibilities:
• Lead SME and researcher for cellular metabolism and RNA:protein interactions – Launched, developed and managed a multiple discipline and highly collaborative (internal and international) project investigating the molecular mechanism of reprogramed colon cancer metabolism by a long non-coding RNA.
• Developed in vivo miRNA therapeutic strategy – Identified a miRNA as potential novel therapeutic target for myelofibrosis; established and tested a strategy to target the miRNA in vivo.
• Characterized and investigated the Type II diabetes phenotype and the molecular mechanism responsible for the phenotype in a long non-coding RNA transgenic mouse
• Trained and mentored graduate students (total of 6).
• Grant writing (on average 5 grants per year).
• Laboratory management duties – handling supply orders and operations. Negotiated with vendor and implemented an optimized ordering system that reduces waiting time for the product by more than a week and increased workflow efficiency
• Dates: Mar 2011 – Nov 2013
• Name and address of employer:M.D. Anderson Cancer Center, Houston, Texas, U.S.A.
• Occupation or position held: Visiting Graduate Research Assistant
• Main activities and responsibilities:
• Tested and validated a long non-coding RNA as potential biomarker for identifying a specific subgroup of breast cancer patients that would benefit from CMF therapy.
• Tested and characterized the expression profile of T-UCRs (Transcribed Ultraconserved Regions) in pancreatic cancer.
• Trained and mentored undergraduate students (total of 5).
• Optimized cell migration and invasion protocols that reduced supply usage cost by 25%, increased result accuracy by 40% and has become standard protocol in the laboratory.
• Dates: Nov 2009 – Mar 2011
• Name and address of employer: Oncological Institute Cluj-Napoca, Romania
• Type of business or sector: Research
• Occupation or position held: Graduate Research Assistant
• Main activities and responsibilities:
• Investigated the protein coding gene profile of breast cancer patients before and after chemotherapy.
• Described to patients the research study and mediated approval for sample collection.
• Dates: Oct 2008 – Feb 2009
• Name and address of employer: InnoChemTech, Braunschweig, Germany
• Occupation or position held: Research Intern
• Main activities and responsibilities:
• Designed and performed the organic synthesis of sulfur-nitrogen heterocycle derivatives.
• Outlined strategies for scale-up to pilot study
• Dates: Jun 2006 – Sep 2008
• Name and address of employer: Babes-Bolyai University, Cluj-Napoca, Romania
• Occupation or position held: Research Student
• Main activities and responsibilities:
• Designed and performed the enantioselective synthesis of benzofuran and benzotiophen cyanohydrins.
• Optimized the synthesis by screening various enzymes which increase the yield of enantiomer production by 15%.
Education
• Dates 2009 – 2013
• Institution University of Medicine and Pharmacy Cluj-Napoca, Romania
• Title of qualification awarded Ph.D. in Medical Sciences
• Dates 2004 – 2009
• Institution Babes-Bolyai University, Cluj-Napoca, Romania
• Title of qualification awarded Chemical Engineer, specialized in Biochemical Engineering (cum laude)
• Dates 2000 – 2004
• Institution Moise Nicoara National College, Arad, Romania
• Title of qualification awarded High School Diploma, specialized in Mathematics and Informatics
Personal Skills & Competencies
LANGUAGES
ROMANIAN – NATIVE PROFICIENCY
ENGLISH
• Reading skills excellent
• Writing skills excellent
• Verbal skills excellent
GERMAN
• Reading skills excellent
• Writing skills good
• Verbal skills good
FRENCH
• Reading skills good
• Writing skills basic
• Verbal skills basic
Social Skills & Competencies
Good communication and intercultural skills, interpersonal effectiveness, flexible, positive attitude, team player – competences acquired working in different areas of research, environments as mentioned above, but also from working and collaborating with people with very diverse cultural background.
Organizational Skills & Competencies
Time management, multitasking skills, ability to motivate others, ability to prioritize, strategic thinking – competences acquired by working simultaneously on multiple projects and collaborations, mentoring students and perform laboratory duties.
Technical Skills & Competencies
• Chemistry – organic and enzymatic assisted synthesis, NMR, thin layer chromatography, gas chromatography, high performance liquid chromatography.
• Molecular biology – gene cloning, gene expression analysis (protein coding gens and non-coding RNA genes)(, PCR, RNA:protein interaction assays, Western, Northern and Southern Blot, microarray, RNAi.
• Cell culture – mammalian cell culture experience, including cell viability assays, transfections and metabolic assays.
• Animal models – xenografts and transgenic mouse models.
DRIVING LICENCE(S) B